物质信息
ID:397106
名称和标识
IUPAC标准名
(2S)-2-hydroxybutanedioic acid; N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide
别名
SU-11248Sunitinib MalateSutentN-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide Malate
IUPAC传统名
(-)-malic acid; sunitinib
数据登录号
CAS号
描述信息
A multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Antineoplastic.
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参考文献
• Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003)
• Sun, L., et al.: J. Med. Chem., 46, 1116 (2003)
• Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2003)
• Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2003)