物质信息
ID:396837
名称和标识
IUPAC标准名
(1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadecan]-6'-ene-5,5'-dione
IUPAC传统名
spironolactone
别名
Spironolactone(7α,7α)-7-(Acetylthyo)-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid γ-LactoneAdactone7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17-carbolactoneSC-9420
数据登录号
CAS号
化合物性质
安全信息
MSDS下载
保存条件
Refrigerator
理化性质
熔点
205-207°C
溶解度
Chloroform
Methanol
外观
White to Off White Soli-
产品相关信息
质检报告
描述信息
It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia
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参考文献
• Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975)