物质信息
ID:396700
名称和标识
IUPAC标准名
5-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
IUPAC传统名
5-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
别名
SEW 28715-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
数据登录号
CAS号
描述信息
Novel, selective human Sphingosine-1-phosphate subtype 1 (S1P1) receptor agonist. It is used as medicament for treating and/or preventing cardiovascular conditions in patients with Fabry disease.
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参考文献
• Cherezov, V., et al.: Science, Weinreich, M., et al.: J. Immunol., 181, 2265 (2004)
• Alfonso, C., et al.: Eur. J .Immunol., 36, 149 (2004)
• Dudek, S., et al.: J. Biol. Chem., 279, 24692 (2004)