物质信息
ID:396395
名称和标识
IUPAC传统名
rilpivirine
IUPAC标准名
4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile
别名
RilpivirineR 2784744-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrileTMC 278
数据登录号
CAS号
描述信息
A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
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参考文献
• Sun, et al.: J. Med. Chem., 41, 4648 (1998)
• Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (1998)