物质信息
ID:396137
名称和标识
IUPAC标准名
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
IUPAC传统名
regorafenib
别名
4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamideRegorafenib 4-[4-[N’-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide
数据登录号
CAS号
描述信息
It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
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参考文献
• Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)