物质信息
ID:390402
名称和标识
IUPAC传统名
2-methoxyestradiol
别名
2-Hydroxyestradiol 2-methyl etherNSC 659853Panzem(17β)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol2-Methoxy 17β-Estradiol2-Methoxyestra-1,3,5(10)-triene-3,17β-diol2-Methoxyestradiol
IUPAC标准名
(1S,10R,11S,14S,15S)-4-methoxy-15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-triene-5,14-diol
数据登录号
CAS号
化合物性质
产品相关信息
质检报告
理化性质
溶解度
Chloroform
Methanol
外观
Off-White Solid
熔点
188-190°C
安全信息
MSDS下载
保存条件
-20°C Freezer
描述信息
2-Methoxy 17β-Estradiol is a natural metabolite of 17β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. 2-Methoxy 17β-Estradiol binds to the colchicine binding site of tubulin, and has been suggested to func
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参考文献
• D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1995)
• Forsis, T., et al.: Nature, 368, 237 (1994)
• Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995)