物质信息
ID:389418
名称和标识
IUPAC标准名
propan-2-yl (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
IUPAC传统名
latanaprost
别名
trans-Latanoprost5,6-trans-Latanoprost(5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester(5E)-Latanoprost
数据登录号
CAS号
描述信息
Prostaglandin analog; prodrug of active acid metabolite. It is a synthetic derivative of the natural prostaglandin PGF2α, used as an anti-glaucoma agent that is effective in various types of glaucoma and ocular hypertension.
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参考文献
• Resul, B., et al.: J. Med. Chem., 36, 2242 (1993)
• Holmstrom, S., et al.: Curr. Med. Res. Op., 21, 1875 (1993)
• Toris, C., et al.: Ophthalmology, 100, 1297 (1993)