物质信息
ID:388749
名称和标识
IUPAC标准名
5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC传统名
5-iodouracil
别名
5-Iodouracil5-Iodo-2,4-dihydroxypyrimidine5-Iodouracil5-Iodo-2,4(1H,3H)-pyrimidinedione5-Iodopyrimidine-2,4-diolNSC 578485-Iodo-2,4-pyrimidinedione
数据登录号
CAS号
描述信息
5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher pre
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参考文献
• Turner, D.P. et al.: Cancer Res., 66, 7686 (2000)
• Meisenheimer, K. et al.: Meth. Enzymol., 318, 88 (2000)
• Klecker, R.W. Jr. et al.: Cancer Chemother. Pharmacol., 48, 407 (2000)