Present in most mammalian tissues; primarily stored in mast cells and basophils. Exhibits multiple biological effects through at least 3 specific receptors. Induces bronchoconstriction and vasodilation; stimulates gastric acid secretion; and acts as a neu
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参考文献
• Hill, S.J., et al.: Pharmacol. Rev., 49, 253 (1910)
• Dale, H.H., et al.: J. Physiol., 41, 318 (1910)
• Oosting, E., et al.: Clin. Exp. Allergy, 20, 349 (1910)