物质信息
ID:386572
(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester
名称和标识
IUPAC标准名
1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
IUPAC传统名
1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
别名
N-tert-Butoxycarbonyl-L-hydroxyproline Methyl EsterMethyl (4R)-N-Boc-4-hydroxy-L-prolinate(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester(2S,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S-trans)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic Acid Methyl Ester(2S,4R)-1-Boc-4-hydroxy-L-proline Methyl Ester
数据登录号
CAS号
化合物性质
产品相关信息
质检报告
理化性质
溶解度
DMF
Ethyl Acetate
Chloroform
Dichloromethane
外观
Clear Colourless Oil
安全信息
MSDS下载
描述信息
(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.
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参考文献
• Freer, R., et al.: Biochemistry, 21, 257 (1982)
• Cavicchioni, G., et al.; Bioorg. Chem., 34, 298 (1982)
• Selvatici, R., et al.: Eur. J. Pharmacol., 534, 1 (1982)
• Higgins, J., et al.: J. Med. Chem., 39, 1013 (1982)