物质信息
ID:384988
S-Ethyl N-[4-Triflurormethyl)phenyl]isothio Urea, Hydrochloride
名称和标识
IUPAC标准名
N-[4-(trifluoromethyl)phenyl](ethylsulfanyl)methanimidamide hydrochloride
IUPAC传统名
N-[4-(trifluoromethyl)phenyl]ethylsulfanylmethanimidamide hydrochloride
别名
ETPI HClS-Ethyl N-[4-Triflurormethyl)phenyl]isothio Urea, Hydrochloride
数据登录号
CAS号
描述信息
A selective inhibitor of nNOS (NOS I) relative to iNOS (NOS II) (115-fold) and eNOS (NOS III) (29-fold). It also binds competitively with L-Arginine.
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参考文献
• Shearer, B.G., et al.: J. Med. Chem., 40, 12, 1901 (1997)