物质信息
ID:384049
名称和标识
IUPAC传统名
entinostat
IUPAC标准名
pyridin-3-ylmethyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate
别名
Entinostat(Pyridin-3-yl)methyl 4-(2-Aminophenylcarbamoyl)benzylcarbamateMS 275MS 275-27MS 27-275N-(2-Aminophenyl)-4-[N-(pyridine-3-yl-methoxycarbonyl)-aminomethyl]benzamideSNDX 275N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]carbamic Acid 3-Pyridinylmethyl Ester
数据登录号
CAS号
描述信息
Entinostat is an emerging HDACi (histone deacetylase inhibitor). Entinostat is used for treatment of solid tumors and hematologic malignancies.
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参考文献
• Hu, E., et al.: J. Pharmacol. Exp. Ther., 307, 720 (2003)
• Xu, W; Oncogene, 26, 5541 (2003)
• Gojo, I., et al.: Blood, 109, 2781 (2003)
• Maggio, S., et al.: Cancer Res., 64, 2590 (2003)