物质信息
ID:380432
名称和标识
IUPAC标准名
7-({4-[(3-ethynylphenyl)amino]-7-methoxyquinazolin-6-yl}oxy)-N-hydroxyheptanamide
别名
CUDC-1017-[[4-[(3-Ethynylphenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanamide7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide
IUPAC传统名
7-({4-[(3-ethynylphenyl)amino]-7-methoxyquinazolin-6-yl}oxy)-N-hydroxyheptanamide
数据登录号
CAS号
描述信息
CUDC-101 is a potent multi-acting HDAC (histone deacetylase), EGFR (epidermal growth factor receptor), and HER2 ( human epidermal growth factor receptor 2) inhibitor for the treatment of cancer.
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参考文献
• Wang, D., et al.: Med. Chem., 48, 6936 (2005)
• Bali, P., et al.: Clin. Cancer Res., 11, 6382 (2005)
• Mann, B., et al.: Oncologist., 12, 1247 (2005)