物质信息
ID:380407
名称和标识
IUPAC传统名
creatinina
IUPAC标准名
2-imino-1-methylimidazolidin-4-one
别名
1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-4-piperidinecarboxamide Hydrochloride1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-4-piperidinecarboxamide MonohydrochlorideCP 945598 HydrochlorideCP 945598-01CP 945598Otenabant Hydrochloride
数据登录号
CAS号
描述信息
CP 945598 is a selective, high affinity CB1 antagonist (Ki values are 0.7 and 0.12 nM in binding and functional assays respectively). Displays low affinity for CB2 receptors (Ki = 7600 nM).
分子图谱
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参考文献
• Griffith, et al.: J. Med. Chem., 52, 234 (2009)
• Hadcock, et al.: Biochem. Biophys. Res. Commun., 394, 366 (2009)