物质信息
ID:378911
名称和标识
IUPAC传统名
C2-ceramide
IUPAC标准名
N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]acetamide
别名
N-Acetyl-D-sphingosineAcetyl CeramideN-AcetylsphingosineN-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamideC2 Ceramide
数据登录号
CAS号
化合物性质
理化性质
溶解度
Dichloromethane
Chloroform
熔点
87-89°C
外观
White Solid
产品相关信息
质检报告
安全信息
MSDS下载
保存条件
-20°C Freezer
描述信息
A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.
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参考文献
• Inoue, T., et al.: J. Biol. Chem., 284, 9566 (2009)
• Rath, G., et al.: Int. J. Biochem. Cell Biol., 41, 1165 (2009)
• Kang, J., et al.: Bioorg. Med. Chem., 17, 1498 (2009)