物质信息
ID:376830
名称和标识
IUPAC标准名
(3aS)-3a-hydroxy-6-methyl-1-phenyl-1H,2H,3H,3aH,4H-pyrrolo[2,3-b]quinolin-4-one
IUPAC传统名
(S)-blebbistatin
别名
(-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one(-)-Blebbistatin(3aS)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one(S)-(-)-Blebbistatin
数据登录号
CAS号
化合物性质
理化性质
外观
Bright Yellow Solid
溶解度
Ethyl Acetate
Methanol
Chloroform
DMSO
Dichloromethane
熔点
>205°C (dec.)
产品相关信息
质检报告
安全信息
MSDS下载
保存条件
-20°C Freezer
描述信息
Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Blebbistatin also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. Blebbistatin blocks both blebbing and cytokinesis
分子图谱
暂无数据
点击上传数据
参考文献
• Kovacs, M., et al.: J. Biol. Chem., 279, 34 35557 (2004)
• Straight, A.F., et al.: Science, 299, 1743 (2003)
• Duxbury, M.S., et al.: Biochem. Biophys. Res. Commun., 313, 992 (2003)