物质信息
ID:374906
名称和标识
IUPAC标准名
calcium bis((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate)
IUPAC传统名
calcium bis(atorvastatin(1-))
别名
CI 981Atorvastatin Calcium SaltYM 548Atorvastatin HemicalciumLipitor(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium SaltSortisTahor
数据登录号
CAS号
描述信息
A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
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参考文献
• Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993)
• Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (1993)
• Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1993)