物质信息
ID:359942
名称和标识
别名
氨苄西林氨苄青霉素AmpicillinD-(-)-α-Aminobenzylpenicillin
IUPAC标准名
(2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
IUPAC传统名
ampicillin
化合物性质
产品相关信息
纯度
≥98.0% (NT)
杂质
≤1% water
Empirical Formula (Hill Notation)
C16H19N3O4S
安全信息
MSDS下载
GHS警示性声明
P261-P280-P305+P351+P338-P342+P311
危险公开号
36/37/38-42/43
个人保护装置
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECS编号
XH8350000
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
安全公开号
22-26-36/37
欧盟危险性物质标志
有害性 (Xn)GHS警示词
Danger
GHS危险声明
H315-H317-H319-H334-H335
德国WGK号
2
保存温度
2-8°C
理化性质
熔点
208 °C (dec.)(lit.)
比旋光度
[α]20/D +295±5°, c = 0.2% in H2O
溶解度
1 M NH4OH: soluble50 mg/mL, clear, colorless
描述信息
Biochem/physiol Actions
A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Inhibits cell wall synthesis in Escherichia coli1; In the purification of penicillin acylase2; Enhances luminol chemiluminescence.3
A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Inhibits cell wall synthesis in Escherichia coli1; In the purification of penicillin acylase2; Enhances luminol chemiluminescence.3
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