物质信息
ID:358773
名称和标识
IUPAC标准名
3-methyl-3-nitroso-1-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
IUPAC传统名
streptozocin
别名
StreptozocinN-(Methylnitrosocarbamoyl)-α-D-glucosamineStreptozotocin
化合物性质
产品相关信息
Empirical Formula (Hill Notation)
C8H15N3O7
纯度
≥98.0% (HPLC)
安全信息
个人保护装置
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS警示性声明
P201-P308+P313
RTECS编号
LZ5775000
保存温度
-20°C
欧盟危险性物质标志
有毒 (T)GHS危险声明
H350
安全公开号
53-45
德国WGK号
3
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
MSDS下载
GHS警示词
Danger
危险公开号
45
理化性质
熔点
121 °C (dec.)(lit.)
描述信息
Biochem/physiol Actions
An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets; induces death of insulin-secreting cells, producing an animal model of diabetes. Potent DNA methylating agent that induces chromosomal breakage.1 Cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.
An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets; induces death of insulin-secreting cells, producing an animal model of diabetes. Potent DNA methylating agent that induces chromosomal breakage.1 Cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.
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