物质信息
ID:354553
名称和标识
IUPAC传统名
sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
IUPAC标准名
sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
别名
Cefotaxim sodium salt 钠盐Cefotaxime sodium salt 钠盐Cefotaxime sodium saltCefotaxim sodium salt
化合物性质
安全信息
GHS危险声明
H317-H334
安全公开号
22-36/37
GHS警示词
Danger
GHS警示性声明
P261-P280-P342+P311
RTECS编号
XI0250000
MSDS下载
个人保护装置
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
保存温度
2-8°C
危险公开号
42/43
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
德国WGK号
2
欧盟危险性物质标志
有害性 (Xn)产品相关信息
杂质
≤5% water
纯度
≥98.0% (TLC)
Empirical Formula (Hill Notation)
C16H16N5NaO7S2
理化性质
溶解度
H2O: soluble50 mg/mL, clear, light yellow
描述信息
Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
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