物质信息
ID:351686
名称和标识
IUPAC传统名
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
IUPAC标准名
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
别名
辣椒碱Capsaicin8-甲基-N-香草基-反-6-壬烯酰胺8-Methyl-N-vanillyl-trans-6-nonenamide
化合物性质
安全信息
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
急性毒性（口服，皮肤接触，吸入），类别1,2,3
MSDS下载
联合国危险货物等级
6.1
RID/ADR
UN 2811 6.1/PG 2
危险公开号
25-37/38-41-42/43
GHS警示词
Danger
GHS危险声明
H301-H315-H317-H318-H334-H335
欧盟危险性物质标志
有毒 (T)RTECS编号
RA8530000
个人保护装置
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
安全公开号
22-26-28-36/39-45
保存温度
2-8°C
GHS警示性声明
P261-P280-P301+P310-P305+P351+P338-P342+P311
联合国危险货物编号
2811
联合国危险货物包装类别(PG)
2
德国WGK号
3
理化性质
闪点
113 °C
235.4 °F
熔点
62-65 °C
62-65 °C(lit.)
产品相关信息
纯度
≥50% (HPLC)
生物来源
from Capsicum sp.
杂质
~35% dihydrocapsaicin
线性分子式
(CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)
药理学性质
相关基因信息
human ... CYP1A2(1544), TRPV1(7442)rat ... Trpv1(83810), Trpv4(66026)
描述信息
包装
1, 5 g in glass bottle
100 mg in glass bottle
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
1, 5 g in glass bottle
100 mg in glass bottle
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
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