物质信息
ID:351232
名称和标识
IUPAC传统名
sparfloxacin
IUPAC标准名
5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
别名
司帕沙星5-氨基-1-环丙基-7-(顺式-3,5-二甲基-1-哌嗪基)-6,8-二氟-1,4-二氢-4-氧代-3-喹啉羧酸5-Amino-1-cyclohexyl-7-(cis-3,5-dimethylpiperazino)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acidSparfloxacin
化合物性质
安全信息
欧盟危险性物质标志
刺激性 (Xi)危险公开号
36/37/38
德国WGK号
2
GHS危险声明
H315-H319-H335
MSDS下载
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
GHS警示性声明
P261-P305+P351+P338
RTECS编号
VB1986500
GHS警示词
Warning
安全公开号
26-36
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
产品相关信息
Empirical Formula (Hill Notation)
C19H22F2N4O3
纯度
≥98.0% (HPLC)
药理学性质
相关基因信息
human ... KCNH1(3756), TOP2A(7153)
描述信息
Biochem/physiol Actions
Inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. Used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation.
Other Notes
Antibacterial agents against respiratory tract infections2
Application
Sparfoxacin is a fluoroquinolone antibiotic used to study antimicrobial activity against mycobacteria and respiratory tract infections 1.
Inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. Used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation.
Other Notes
Antibacterial agents against respiratory tract infections2
Application
Sparfoxacin is a fluoroquinolone antibiotic used to study antimicrobial activity against mycobacteria and respiratory tract infections 1.
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