物质信息

ID:351213

1,8-Dihydroxy-3-methylanthraquinone

名称和标识
IUPAC传统名
turkey rhubarb
IUPAC标准名
1,8-dihydroxy-3-methyl-9,10-dihydroanthracene-9,10-dione
别名
1,8-Dihydroxy-3-methylanthraquinoneChrysophanic acid
数据登录号
CAS号
PubChem SID
Beilstein号
化合物性质
药理学性质
相关基因信息
human ... ELA2(1991)
安全信息
GHS警示词
Warning
德国WGK号
3
MSDS下载
GHS危险声明
H315-H319
GHS警示性声明
P305+P351+P338
安全公开号
26
GHS危险品标识
GHS07
急性毒性(口服,皮肤接触,吸入),类别4
皮肤刺激,类别2
眼刺激,类别2
皮肤过敏,类别1
特定目标器官毒性 -一次接触,类别3
欧盟危险性物质标志
刺激性 刺激性 (Xi)
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
危险公开号
36/38
RTECS编号
CB6725000
产品相关信息
Empirical Formula (Hill Notation)
C15H10O4
纯度
98%
描述信息
包装
1 g in glass bottle
50 mg in glass bottle
Application
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Biochem/physiol Actions
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway 1. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus 2.
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