物质信息
ID:350677
名称和标识
IUPAC传统名
birthwort
IUPAC标准名
6-methoxy-9-nitro-14,16-dioxatetracyclo[8.7.0.02,7.013,17]heptadeca-1(17),2,4,6,8,10,12-heptaene-11-carboxylic acid
别名
TR 1736Aristolochic acid I
化合物性质
安全信息
GHS警示性声明
P301+P310
德国WGK号
3
RID/ADR
UN 1544 6.1/PG 3
联合国危险货物包装类别(PG)
3
RTECS编号
CF3325000
联合国危险货物编号
1544
GHS警示词
Danger
危险公开号
25
联合国危险货物等级
6.1
欧盟危险性物质标志
有毒 (T)安全公开号
7-35-45
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
保存温度
2-8°C
MSDS下载
个人保护装置
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS危险声明
H301
理化性质
溶解度
ethanol: soluble
DMSO: soluble
外观
yellow powder
产品相关信息
Empirical Formula (Hill Notation)
C17H11NO7
描述信息
Biochem/physiol Actions
Potent phospholipase A2 inhibitor, including calcium ionophore-induced phospholipase A2 activity in neutrophils. Kidney tumor initiator in experimental animal model.1
Application
Aristolochic acid I is a potent phospholipase A2 inhibitor. Aristolochic acid I induces tumor formation in rat kidneys and apoptosis in human renal proximal tubular epithelial cells.
Potent phospholipase A2 inhibitor, including calcium ionophore-induced phospholipase A2 activity in neutrophils. Kidney tumor initiator in experimental animal model.1
Application
Aristolochic acid I is a potent phospholipase A2 inhibitor. Aristolochic acid I induces tumor formation in rat kidneys and apoptosis in human renal proximal tubular epithelial cells.
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