物质信息
ID:350012
名称和标识
IUPAC标准名
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
IUPAC传统名
forskolin
别名
Coleonol7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-oneForskolinColforsin
化合物性质
产品相关信息
Empirical Formula (Hill Notation)
C22H34O7
级别
for molecular biology
产品线
BioReagent
纯度
≥98%
生物来源
from Coleus forskohlii
药理学性质
相关基因信息
human ... OPRK1(4986), SLC2A10(81031), TNF(7124)
安全信息
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS危险声明
H312
欧盟危险性物质标志
有害性 (Xn)GHS警示性声明
P280
德国WGK号
3
MSDS下载
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
GHS警示词
Warning
危险公开号
21
RTECS编号
QL6150000
安全公开号
22-36/37
描述信息
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Analysis Note
Tested for inhibition of interleukin-2 production by Jurkat cells.
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
Live Chat and Frequently Asked Questions are available for this Product.
Analysis Note
Tested for inhibition of interleukin-2 production by Jurkat cells.
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
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