物质信息
ID:349670
名称和标识
IUPAC标准名
7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-2H-chromen-2-one
IUPAC传统名
7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]chromen-2-one
别名
Aurapten7-Geranyloxycoumarin7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-oneAuraptene
化合物性质
产品相关信息
纯度
≥98% (HPLC)
Empirical Formula (Hill Notation)
C19H22O3
理化性质
溶解度
DMSO: >20 mg/mL
外观
white to off-white powder
安全信息
描述信息
Biochem/physiol Actions
Auraptene is an estrogen receptor modulator that also acts as an ACAT inhibitor. It displays anti-tumor effects in several xenograft and chemically-induced murine tumor models. Auraptene induces apoptosis and is anti-proliferative in cancer cell lines. It has agonistic properties against PPARs, and interferes with lipid and cholesterol production by inhibiting ACAT (IC50 = 4 uM).
Auraptene is an estrogen receptor modulator that also acts as an ACAT inhibitor. It displays anti-tumor effects in several xenograft and chemically-induced murine tumor models. Auraptene induces apoptosis and is anti-proliferative in cancer cell lines. It has agonistic properties against PPARs, and interferes with lipid and cholesterol production by inhibiting ACAT (IC50 = 4 uM).
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