物质信息
ID:349558
名称和标识
IUPAC标准名
5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione
IUPAC传统名
rosiglitazone
别名
rosiglitazoneRosiglitazone5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
化合物性质
安全信息
理化性质
溶解度
DMSO: ≥10 mg/mL
外观
powder
产品相关信息
纯度
≥98% (HPLC)
≥98% (HPLC)
线性分子式
C18H19N3O3S
描述信息
Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.
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