物质信息
ID:348772
名称和标识
别名
Cryptotanshinone(R)-(-)-1,6,6-Trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione
IUPAC标准名
(14R)-6,6,14-trimethyl-12-oxatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15)-tetraene-16,17-dione
IUPAC传统名
(14R)-6,6,14-trimethyl-12-oxatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15)-tetraene-16,17-dione
化合物性质
安全信息
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
对水环境的危害
急性危害，类别1
慢性危害，类别1,2
GHS危险声明
H301-H410
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
GHS警示词
Danger
RTECS编号
SF8282645
GHS警示性声明
P273-P301+P310-P501
欧盟危险性物质标志
有毒 (T)
环境危害性 (N)MSDS下载
安全公开号
45-60-61
德国WGK号
3
危险公开号
25-50/53
保存温度
2-8°C
理化性质
比旋光度
[α]/D -85.0±3.0°, c = 0.1 in chloroform
产品相关信息
Empirical Formula (Hill Notation)
C19H20O3
纯度
≥90% (HPLC)
描述信息
Biochem/physiol Actions
Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation1 and to inhibit macrophage migration negatively regulate the PI3K pathway.2,3 It has demonstrated activity against several strains of Staphylococcus aureus.4
Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation1 and to inhibit macrophage migration negatively regulate the PI3K pathway.2,3 It has demonstrated activity against several strains of Staphylococcus aureus.4
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