物质信息
ID:347899
名称和标识
IUPAC传统名
troglitazone
IUPAC标准名
5-({4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-yl)methoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione
别名
CS-045Troglitazone(±)-5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione
化合物性质
安全信息
MSDS下载
RTECS编号
XJ5813130
德国WGK号
2
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
产品相关信息
纯度
≥98% (HPLC)
Empirical Formula (Hill Notation)
C24H27NO5S
药理学性质
相关基因信息
human ... PPARA(5465), PPARG(5468)
理化性质
外观
white to yellow solid
溶解度
DMSO: soluble20 mg/mL
描述信息
Biochem/physiol Actions
PPARγ agonist; anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity; induces apoptosis via a p53 pathway.
PPARγ agonist; anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity; induces apoptosis via a p53 pathway.
分子图谱
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参考文献
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