物质信息
ID:346938
名称和标识
IUPAC标准名
4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
IUPAC传统名
4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
别名
ZM 2413854-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol
化合物性质
安全信息
GHS警示性声明
P301+P310
危险公开号
25
GHS危险声明
H301
安全公开号
46
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
GHS警示词
Danger
欧盟危险性物质标志
有毒 (T)MSDS下载
德国WGK号
3
保存温度
room temp
理化性质
外观
white to tan powder
溶解度
DMSO: >15 mg/mL
产品相关信息
纯度
≥98% (HPLC)
Empirical Formula (Hill Notation)
C16H15N7O2
描述信息
Biochem/physiol Actions
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.
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