物质信息

ID:346

名称和标识
商标名
EndiemalumMetarbital [INN-Spanish]Metarbitale [Dcit]MetharbitoneGemonalMetharbutalMetabarbitalMethabarbitalMethabarbitoneMetharbital [INN:Jan]Metharbitalum [INN-Latin]MethylbarbitalGemonilGemonitN-MethylbarbitalEndiemal
IUPAC传统名
metharbital
IUPAC标准名
5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
别名
Metharbital
数据登录号
CAS号
PubChem SID
PubChem CID
化合物性质
理化性质
疏水性(logP)
0.6
溶解度
1980 mg/L
描述信息
Drug Groups
approved
Description
Metharbital was patented in 1905 by Emil Fischer working for Merck. It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy. It has similar properties to phenobarbital.

Indication
Metharbital is used for the treatment of epilepsy.
Pharmacology
Metharbital, a barbiturate, is used for the treatment of short term insomnia. It belongs to a group of medicines called central nervous system (CNS) depressants that induce drowsiness and relieve tension or nervousness. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.
Toxicity
Signs of overdose include confusion (severe), decrease in or loss of reflexes, drowsiness (severe), fever, irritability (continuing), low body temperature, poor judgment, shortness of breath or slow or troubled breathing, slow heartbeat, slurred speech, staggering, trouble in sleeping, unusual movements of the eyes, weakness (severe).
Affected Organisms
Humans and other mammals
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