物质信息
ID:339385
名称和标识
IUPAC标准名
diethyl (bromodifluoromethyl)phosphonate
IUPAC传统名
diethyl bromodifluoromethylphosphonate
别名
Diethyl (bromodifluoromethyl)phosphonate溴氟甲基膦酸二乙酯(Bromodifluoromethyl)phosphonic acid diethyl ester
化合物性质
理化性质
闪点
>113 °C
>235.4 °F
沸点
40-41 °C/0.05 mmHg(lit.)
密度
1.503 g/mL at 25 °C(lit.)
折射率
n20/D 1.417(lit.)
安全信息
产品相关信息
线性分子式
BrCF2P(O)(OC2H5)2
纯度
96%
描述信息
包装
5 g in glass bottle
Application
Reactant for:
• Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3)1
• Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps2
• P-C bond cleavage on basic hydrolysis3
• Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety)4
5 g in glass bottle
Application
Reactant for:
• Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3)1
• Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps2
• P-C bond cleavage on basic hydrolysis3
• Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety)4
分子图谱
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参考文献
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