物质信息

ID:315532

名称和标识
IUPAC标准名
(4-cyanophenyl)boronic acid
IUPAC传统名
4-cyanophenylboronic acid
别名
4-氰基苯硼酸4-Cyanobenzeneboronic acid4-Cyanophenylboronic acid4-Cyanophenylboric acid(p-Cyanophenyl)boronic acid
数据登录号
PubChem SID
化合物性质
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
MSDS下载
德国WGK号
3
产品相关信息
线性分子式
NCC6H4B(OH)2
理化性质
熔点
>350 °C(lit.)
描述信息
Other Notes
含有不定量的酸酐
包装
1 g in glass bottle
10 g in poly bottle
Application
Reactant involved in:
• Oxidative hydroxylation1
• Trifluoromethylation2
• 1,4-Addition reactions3Precursor in the synthesis of inhibitors such as:
• Tpl2 kinase inhibitors4
• P2X7 antagonists used in the treatment of pain5
Reagent used for
• Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water
• Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates
• Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids
• Ferric perchlorate-promoted reaction of fullerenes with various arylboronic acids to give fullerenyl boronic esters
• Phosphine-free Suzuki-Miyaura cross-coupling
• Palladacycles as effective catalysts for multicomponent reaction with allylpalladium-intermediates
• Chan-Lam-type Cu-catalyzed S-arylation of thiols
• Regioselective cross-coupling reactions under modfied Suzuki and Still cross-coupling reactions with Copper catalysis
• Metal-free biaryl coupling in dimethyl carbonate as a solventReagent used for Preparation of
• Himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents
• Trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark
• Antimalarial compounds via Suzuki cross-coupling
• Deoxyuridine derivatives
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参考文献
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