物质信息

ID:286

名称和标识
IUPAC标准名
(3S)-3-[(2R)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-amino-3-[4-(sulfooxy)phenyl]propanamido]-3-hydroxybutanamido]acetamido}-3-(1H-indol-3-yl)propanamido]hexanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid
IUPAC传统名
tymtran
别名
Ceruletide
数据登录号
化合物性质
理化性质
疏水性(logP)
-0.9
描述信息
Drug Groups
approved
Description
Caerulein is a specific decapeptide similar in action and composition to the natural gastrointestinal peptide hormone cholecystokinin. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle.
Indication
Caerulein stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. As such, it is used in paralytic ileus and as diagnostic aid in pancreatic malfunction.
Pharmacology
Caerulein is a specific decapeptide similar in action and composition to the natural gastrointestinal peptide hormone cholecystokinin. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle.
Affected Organisms
Humans and other mammals
Absorption
Absorbed following intravenous administration.
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