物质信息

ID:272

名称和标识
IUPAC标准名
ethyl 3-methyl-2-sulfanylidene-2,3-dihydro-1H-imidazole-1-carboxylate
IUPAC传统名
carbimazole
别名
CarbimazoleCarbimazolum [INN-Latin]CarbethoxymethimazoleCarbimazolAthyromazoleCarbimazol [INN-Spanish, French]Carbinazole
商标名
Neo-MercazoleAtirozidinaBasolestCarbimazol SpofaNeo-TireolCG1CarbotiroidMertiranNeo-ThyreostatNeomercazoleTyrazol
数据登录号
PubChem CID
PubChem SID
化合物性质
理化性质
疏水性(logP)
0.4
描述信息
Drug Groups
approved
Description
An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity. [PubChem]
Indication
For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
Pharmacology
Carbimazole is a carbethoxy derivative of methimazole. Its antithyroid action is due to its conversion to methimazole after absorption. It is used to treat hyperthyroidism and thyrotoxicosis.
Affected Organisms
Humans and other mammals
Protein Binding
85%
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