物质信息

ID:2219

Methoxy arachidonyl fluorophosphonate

名称和标识
IUPAC标准名
(R)-[(5E,8E,11E,14E)-icosa-5,8,11,14-tetraen-1-yl](methoxy)phosphinoyl fluoride
别名
MAFPMethoxy arachidonyl fluorophosphonate
IUPAC传统名
MAFP
数据登录号
PubChem CID
PubChem SID
化合物性质
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描述信息
Drug Groups
experimental
Description
Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values in the low-nanomolar range.
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