物质信息
ID:1857066
名称和标识
IUPAC标准名
4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide
IUPAC传统名
tandutinib
别名
tandutinib(4-(6-methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl)piperazinyl)-N-(4-(methylethoxy)phenyl)carboxamideCT 53518CT-53518CT53518MLN 518MLN-518MLN518
国际非专利药品(INN)
tandutinibtandutinibum
数据登录号
PubChem CID
CAS号
LINCS数据库
Reaxys Registry
ACToR数据库
BKMS React数据库
BRENDA数据库
BRENDA Ligand数据库
CHEMBL
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SureChEMBL数据库
DrugBank ID
BindingDB数据库
KEGG DRUG Database
CHEBI ID
PubChem SID
化合物性质
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描述信息
An N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a 6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl group, while the hydrogen attached to the nitrogen at position 4 is replaced by a (p-isopropoxyphenyl)aminocarbonyl group. Tandutinib is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT.
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参考文献
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