物质信息

ID:184355

名称和标识
别名
氨苄西林氨苄青霉素Ampicillin
IUPAC标准名
(2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
IUPAC传统名
ampicillin
数据登录号
CAS号
Beilstein号
PubChem SID
化合物性质
安全信息
欧盟危险性物质标志
有害性 有害性 (Xn)
GHS危险品标识
GHS08
呼吸道过敏,类别1
生殖细胞突变,类别1A,1B,2
致癌性,类别1A,1B,2
生殖毒性,类别1A,1B,2
特定目标器官毒性 – 一次接触,类别1,2
特定目标器官毒性 – 反复接触,类别1,2
吸入危险,类别1
GHS07
急性毒性(口服,皮肤接触,吸入),类别4
皮肤刺激,类别2
眼刺激,类别2
皮肤过敏,类别1
特定目标器官毒性 -一次接触,类别3
安全公开号
22-26-36/37
GHS警示词
Danger
GHS警示性声明
P261-P280-P305+P351+P338-P342+P311
保存温度
2-8°C
GHS危险声明
H315-H317-H319-H334-H335
危险公开号
36/37/38-42/43
德国WGK号
2
个人保护装置
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECS编号
XH8350000
理化性质
熔点
208 °C (dec.)(lit.)
溶解度
1 M NH4OH: soluble50 mg/mL
产品相关信息
纯度
96.0-100.5% (anhydrous basis)
适用性
suitable for 1694 per US EPA
描述信息
Frequently Asked Questions
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Biochem/physiol Actions
A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Application
Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid 1,2,3,4.
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