物质信息
ID:184328
名称和标识
别名
SAM chloride dihydrochlorideActive methionineAdoMetS-(5′-Adenosyl)-L-methionine chloride dihydrochloride
IUPAC标准名
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium chloride
IUPAC传统名
SAMe chloride
化合物性质
产品相关信息
纯度
≥80%
运输包装
dry ice
生物来源
from yeast (L-Methionine enriched)
安全信息
德国WGK号
3
保存温度
-20°C
理化性质
溶解度
H2O: soluble100 mg/mL
描述信息
Analysis Note
Purity based on UV and HPLC.
Caution
This material is 80-90% pure when prepared, but is very unstable. As much as 10% purity loss per day at 25 °C has been noted.
Biochem/physiol Actions
Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
Purity based on UV and HPLC.
Caution
This material is 80-90% pure when prepared, but is very unstable. As much as 10% purity loss per day at 25 °C has been noted.
Biochem/physiol Actions
Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
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