物质信息
ID:183945
名称和标识
别名
Carboplatincis-Diammine(1,1-cyclobutanedicarboxylato) platinum
IUPAC标准名
6,8-dioxa-7-platinaspiro[3.5]nonane-5,9-dione diamine
IUPAC传统名
6,8-dioxa-7-platinaspiro[3.5]nonane-5,9-dione diamine
化合物性质
安全信息
个人保护装置
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
德国WGK号
3
安全公开号
53-22-26-36/37/39-45
GHS危险声明
H302+H312+H332-H317-H334-H360
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS警示词
Danger
危险公开号
46-61-20/21/22-42/43
GHS警示性声明
P201-P261-P280-P308+P313
RTECS编号
TP2300000
欧盟危险性物质标志
有毒 (T)描述信息
Biochem/physiol Actions
Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death.
Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death.
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