物质信息

ID:1828786

名称和标识
IUPAC标准名
2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide hydrochloride
IUPAC传统名
benserazide hydrochloride
别名
benserazide hydrochloride2'-(2,3,4-trihydroxybenzyl)-DL-serinohydrazide monohydrochloride3-hydroxy-1-oxo-1-[2-(2,3,4-trihydroxybenzyl)hydrazinyl]propan-2-aminium chlorideDL-serine 2-(2,3,4-trihydroxybenzyl)hydrazine hydrochlorideRo 4-4602/001benserazide HCl
数据登录号
PubChem CID
Reaxys Registry
ACToR数据库
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KEGG DRUG Database
CHEBI ID
PubChem SID
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描述信息
A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone.
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