物质信息
ID:182768
名称和标识
IUPAC标准名
3-(2-chloroethyl)-1-(4-methylcyclohexyl)-3-nitrosourea
别名
司莫司汀SemustineMethyl-CCNUN-(2-氯乙基)-N′-(4-甲基环己基)-N-亚硝脲
IUPAC传统名
semustine
化合物性质
安全信息
GHS警示词
Danger
RID/ADR
UN 2811 6.1/PG 2
危险公开号
45-46-23/24/25-36/37/38
安全公开号
53-22-26-36/37/39-45
联合国危险货物编号
2811
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
欧盟危险性物质标志
有毒 (T)GHS警示性声明
P201-P261-P264-P280-P301+P310-P305+P351+P338
RTECS编号
YS5000000
GHS危险声明
H300-H311-H315-H319-H331-H335-H350-H360
联合国危险货物等级
6.1
个人保护装置
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
联合国危险货物包装类别(PG)
2
德国WGK号
3
描述信息
Application
Commonly used in pharmacological studies involving:
• Nutrient-sensitized screening for drugs that shift the energy metabolism from mitchondrial respiration to glycolysis1
• CEOP regimen with semustine used as induction chemotherapy in patients with lymphoma2
• Investigations into its use for chemotherapy3,4
Commonly used in pharmacological studies involving:
• Nutrient-sensitized screening for drugs that shift the energy metabolism from mitchondrial respiration to glycolysis1
• CEOP regimen with semustine used as induction chemotherapy in patients with lymphoma2
• Investigations into its use for chemotherapy3,4
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