物质信息
ID:182689
名称和标识
IUPAC标准名
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
IUPAC传统名
tetracycline hydrochloride
别名
四环素 盐酸盐Tetracycline hydrochloride
化合物性质
安全信息
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS警示词
Warning
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
危险公开号
36/37/38
保存温度
-20°C
安全公开号
26-36
德国WGK号
2
欧盟危险性物质标志
刺激性 (Xi)RTECS编号
QI9100000
GHS警示性声明
P261-P305+P351+P338
GHS危险声明
H315-H319-H335
产品相关信息
适用性
suitable for cell culture
杂质
endotoxin, tested
理化性质
溶解度
H2O: soluble10 mg/mL (as a stock solution. Stock solutions should be filtered sterilized and stored at -20°C. Stable at 37°C for 4 days.)
外观
powder
熔点
220-223 °C(lit.)
描述信息
Application
Used in tetracycline controlled gene expression systems (gene switches) such a the tet-on and tet-off systems. Recommended for use in cell culture applications at 10 mg/L.
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.Mode of Resistance: Loss of cell wall permeability.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Used in tetracycline controlled gene expression systems (gene switches) such a the tet-on and tet-off systems. Recommended for use in cell culture applications at 10 mg/L.
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.Mode of Resistance: Loss of cell wall permeability.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
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