物质信息
ID:1826506
名称和标识
别名
SN-3810-Hydroxy-7-ethylcamptothecin7-Ethyl-10-hydroxy-20(S)-camptothecin7-Ethyl-10-hydroxycamptothecinNK 012NK-012SN 38SN 38 lactoneSN-38
IUPAC标准名
(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
IUPAC传统名
(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
数据登录号
CAS号
维基百科标题
PubChem CID
KEGG ID
PubMed文献链接
Reaxys Registry
ACToR数据库
BKMS React数据库
BRENDA数据库
BRENDA Ligand数据库
CHEMBL
CompTox数据库
PDB数据库
SureChEMBL数据库
Rhea数据库
HMDB数据库
PDBeChem数据库
ArrayExpress (Gene Expression Altlas)
CHEBI ID
PubChem SID
化合物性质
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描述信息
A member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself.
分子图谱
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参考文献
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