物质信息
ID:182603
名称和标识
IUPAC标准名
(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
IUPAC传统名
armes
别名
Ara-AAdenine 9-β-D-arabinofuranoside9-β-D-ArabinofuranosyladenineVidarabine
化合物性质
安全信息
欧盟危险性物质标志
有害性 (Xn)GHS警示性声明
P281
RTECS编号
AU6200000
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
GHS警示词
Warning
GHS危险声明
H361
危险公开号
63
保存温度
-20°C
安全公开号
36/37
德国WGK号
3
产品相关信息
纯度
≥99%
药理学性质
相关基因信息
mouse ... Ahcy(269378)
描述信息
Application
Used to study the roles of AMP-activated protein kinase (AMPK) in cell signaling.
Biochem/physiol Actions
Cell-permeable adenylate cyclase inhibitor; in detergent-dispersed rat brain preparation, IC50 = 30 μM. Clinically significant antiviral agent, especially against herpes simplex (HSV),1 by inhibition of DNA polymerase.
Used to study the roles of AMP-activated protein kinase (AMPK) in cell signaling.
Biochem/physiol Actions
Cell-permeable adenylate cyclase inhibitor; in detergent-dispersed rat brain preparation, IC50 = 30 μM. Clinically significant antiviral agent, especially against herpes simplex (HSV),1 by inhibition of DNA polymerase.
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参考文献
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