物质信息
ID:1824683
名称和标识
IUPAC传统名
entinostat
别名
entinostatBAY 86-5274BAY86-5274MS 27-275MS 275MS-27-275MS-275N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamideN-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl esterSNDX 275SNDX-275
国际非专利药品(INN)
entinostatentinostatum
IUPAC标准名
(pyridin-3-yl)methyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate
数据登录号
PubChem CID
CAS号
维基百科标题
LINCS数据库
PubMed文献链接
Reaxys Registry
ACToR数据库
CHEMBL
CompTox数据库
SureChEMBL数据库
BindingDB数据库
KEGG DRUG Database
CHEBI ID
PubChem SID
化合物性质
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描述信息
A member of the class of benzamides resulting from the formal condensation of the carboxy group of the pyridin-3-ylmethyl carbamate derivative of p-(aminomethyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an inhibitor of histone deacetylase isoform 1 (HDAC1) and isoform 3 (HDAC3).
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参考文献
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