物质信息
ID:182090
名称和标识
IUPAC传统名
3-[3-(4,4-diphenylpiperidin-1-yl)propyl] 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
IUPAC标准名
3-[3-(4,4-diphenylpiperidin-1-yl)propyl] 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
别名
S(+)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(4,4-diphenyl-1-piperidinyl)-propyl methyl ester hydrochlorideS(+)-Niguldipine hydrochloride
化合物性质
理化性质
比旋光度
[α]22/D +14.62°, c = 0.13 in methanol(lit.)
溶解度
DMSO: soluble13 mg/mL
H2O: insoluble
dilute aqueous acid: insoluble
ethanol: soluble16 mg/mL
methanol: soluble8 mg/mL
外观
yellow solid
安全信息
德国WGK号
3
保存温度
-20°C
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
描述信息
Caution
Photosensitive. This compound adsorbs strongly to plastic.
Biochem/physiol Actions
α1A-adrenoceptor antagonist; antihypertensive agent; L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channels.
Photosensitive. This compound adsorbs strongly to plastic.
Biochem/physiol Actions
α1A-adrenoceptor antagonist; antihypertensive agent; L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channels.
分子图谱
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参考文献
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