物质信息
ID:181952
名称和标识
IUPAC传统名
pregnenolone
IUPAC标准名
1-[(1S,2R,5S,10S,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-7-en-14-yl]ethan-1-one
别名
5-Pregnen-3β-ol-20-one3β-Hydroxy-5-pregnen-20-onePregnenolone
化合物性质
安全信息
RTECS编号
TU5560700
德国WGK号
3
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
产品相关信息
纯度
≥98%
药理学性质
相关基因信息
human ... SERPINA6(866)rat ... Ar(24208)
描述信息
Biochem/physiol Actions
One of a small number of "neurosteroids," steroids synthesized in the brain rather than peripheral sources. Decreased levels of these neurosteroids has been implicated in rodent cognitive decline with age, but studies in humans have been contradictory.1
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P9129.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
One of a small number of "neurosteroids," steroids synthesized in the brain rather than peripheral sources. Decreased levels of these neurosteroids has been implicated in rodent cognitive decline with age, but studies in humans have been contradictory.1
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P9129.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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参考文献
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