物质信息
ID:181847
名称和标识
IUPAC传统名
(3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic acid
IUPAC标准名
(3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic acid
别名
Z-VAD-FMK, Non-methylatedZ-Val-Ala-Asp fluoromethyl ketone
数据登录号
MDL号
化合物性质
理化性质
外观
powder
产品相关信息
运输包装
dry ice
纯度
≥90% (TLC)
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度
-20°C
德国WGK号
3
描述信息
Amino Acid Sequence
Z-Val-Ala-Asp-OMe-FMK
Biochem/physiol Actions
Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).
Z-Val-Ala-Asp-OMe-FMK
Biochem/physiol Actions
Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).
分子图谱
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参考文献
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