物质信息

ID:181447

MolImageID:132760

Apelin-13 trifluoroacetate salt

Sigma Aldrich
名称和标识
别名
Apelin-13 trifluoroacetate saltPrepro-65-77-Apelin
IUPAC传统名
(2S)-2-{[(2S)-1-[(2S)-2-{[(2S)-1-{2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-(3H-imidazol-4-yl)propanamido]hexanamido]acetyl}pyrrolidin-2-yl]formamido}-4-(methylsulfanyl)butanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanoic acid; trifluoroacetic acid
IUPAC标准名
(2S)-2-{[(2S)-1-[(2S)-2-{[(2S)-1-{2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-(1H-imidazol-5-yl)propanamido]hexanamido]acetyl}pyrrolidin-2-yl]formamido}-4-(methylsulfanyl)butanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanoic acid; trifluoroacetic acid
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化合物性质
安全信息
德国WGK号
3
保存温度
-20°C
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
产品相关信息
纯度
≥95%
药理学性质
相关基因信息
human ... APLN(8862)
描述信息
Amino Acid Sequence
Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
Biochem/physiol Actions
Synthetic endogenous peptide agonist for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). This peptide exerted an acidification-rate-promoting activity in CHO cells expressing the APJ receptor with a median effective concentration (EC50) value of 0.37 nM. Blocks HIV-1 and HIV-2 entry into cells expressing the APJ receptor.
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